WebOct 1, 1997 · In studies with THP-1 human myelomonocytic cells and 32D mouse myeloid cells, which are IRS-defective, we found that the IFN-alpha-regulated activation of Stat-1, Stat-2, and Stat-3 does not require the function of the IRS-system. Furthermore, THP-1 cells are responsive to the protective effect of IFN-alpha against vesicular stomatitis virus. WebOct 1, 1997 · In studies with THP-1 human myelomonocytic cells and 32D mouse myeloid cells, which are IRS-defective, we found that the IFN-alpha-regulated activation of Stat-1, …
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WebNov 1, 2024 · 1. Introduction. Steroid hormones have different effects on various tissues such as gonads and the nervous system. In addition to their hormonal role in reproductive … WebApr 8, 2024 · In the present study, using THP-1 human leukemic monocytes, expressing αvβ3 integrin in their cell membrane, we focused on the crosstalk between thyroid hormones and either IGF-1 or monocyte chemoattractant protein-1 (MCP-1), studying cell migration and proliferation stimulated by the two chemokines, and the role of αvβ3 integrin, using … cod waffen schnell leveln
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WebApr 8, 2024 · Our results show that IGF-1 is a potent chemoattractant in THP-1 monocytes, stimulating cell migration, and thyroid hormone inhibits the effect through αvβ3 integrin. Thyroid hormone also inhibits IGF-1-stimulated cell proliferation through αvβ3 integrin, an example of a crosstalk between genomic and non-genomic effects. WebDec 1, 2013 · These discrepancies may be explained at least in part by the diverse immunological assay variations, different concentrations of hormones, or different cell differentiation techniques. 38 Indeed, PMA-treated THP-1 monocytes in the previous study were differentiated into macrophage-like cells 36 whereas the current study used VitD3 to … WebMar 12, 2007 · A hormone called THP is normally released in response to stress. It usually behaves like a tranquiliser, acting at sites in the brain that calm brain activity and, in adults … cod waffen auf gold