Web51 rows · Vesicant: Medication that may causes severe and/or irreversible tissue injury and necrosis. Irritant: Medication that can cause local inflammatory reactions at the infusion site, which may include: burning, swelling, pain, inflammation, tightness, or phlebitis. Clinical … Serotonin (5-HT3) antagonist. Dolasetron (Anzemet) 100 mg PO once on day 1 … WebVesicants: Drugs capable of causing pain, inflammation and blistering of the local skin, underlying flesh and structures leading to tissue necrosis and death Irritants: …
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Web1. Vesicants are administered first with no difference given for peripheral versus central line administration. 2. Follow the order given by the physician. If the regimen includes a vesicant, then follow #1 and give the remaining drugs in the order written. 3. Oncology clinical pharmacists review the orders and make recommendations to the WebJun 13, 2016 · Cyclophosphamide (Cytoxan) This drug can treat a variety of cancers, including lymphoma and cancer of the breast and lung. Cyclophosphamide targets the DNA of cancer cells and signals them to … five nights at in
Medications with irritant or vesicant properties
WebApr 9, 2009 · Her oncologist suggested adjuvant chemotherapy (four cycles of cyclophosphamide [Cytoxan] at 600 mg/m2 plus doxorubicin [Adriamycin] at 60 mg/m2) followed by local radiation therapy. The patient, “JB,” is a 68-year-old woman who underwent a right lumpectomy and axillary node dissection for stage II breast cancer. WebVesicant/irritant properties: Doxorubicin is a vesicant and can cause significant tissue damage if an extravasation occurs. For peripheral infusions, the IV line should be … WebJan 15, 2007 · Agent Diluent (preferred is bolded) Inpatient Diluent Volume Outpatient Diluent Volume (if different) Administration Rate Comments Dacarbazine NS or D5W 250 - 500 mL 30-60 min Vesicant; Protect from light; Decomposed drug turns pink Dactinomycin D5W or NS 50 mL Undiluted drug IVPB over 15 min Vesicant; Protect from light … five nights at humpty dumpty\u0027s